Research on how intestinal microbiota fights against food-borne pathogens.

The COL_RES network is made up of a group of world-leading researchers investigating the mechanisms by which the gut microbiota protects against serious foodborne pathogens (Salmonella, E. coli, Listeria, Citrobacter and Campylobacter).

As a result, it will lead to the identification of new-generation probiotics that can protect against multiple infectious agents.

Through cross-sectoral affiliations between industry and academia, the network offers state-of-the-art training for early-stage researchers (ESRs), preparing them for problem-solving and entrepreneurial roles in industry and society and supporting cutting-edge research in infectious diseases in the European Union.

Food and waterborne diseases cause 23 million illnesses in Europe with 5,000 deaths a year and represent a growing health challenge. Through the study of different pathogens, COL_RES carries out a multi-omic approach to identify common mechanisms of action by which the members of the intestinal microbiota provide a natural barrier to infection through the phenomenon of colonisation resistance.

COL_RES uses a strategy based on the exploitation of existing pre-clinical research models in network laboratories, combined with phageomics, metagenomics, metabolomics and bioinformatics to generate multi-omic data and discover pathogen-specific mechanisms and the common mechanisms by which the gut microbiota protects against foodborne pathogens.

Likewise, COL_RES will enable the selection of new-generation specific probiotic candidates that can protect against foodborne infections.

The COL_RES network, coordinated by the University of Cork, has the participation of Eurecat through the Omic Sciences Unit, which develops computational analysis tools for metabolomics data from the microbiota.


General details


COL_RES – Colonization resistance: training and research towards microbiome derived solutions to foodborne disease

Project reference


Programme and call for tender

Project funded by the Horizon 2020 program of the European Union within the Marie Skłodowska-Curie Actions (MSCA) – Innovative Training Networks call

More information about the project