{"id":117768,"date":"2021-10-27T15:50:37","date_gmt":"2021-10-27T14:50:37","guid":{"rendered":"https:\/\/eurecat.org\/?post_type=avada_portfolio&p=117768"},"modified":"2021-11-22T09:38:31","modified_gmt":"2021-11-22T08:38:31","slug":"alternative","status":"publish","type":"avada_portfolio","link":"https:\/\/eurecat.org\/es\/portfolio-items\/alternative\/","title":{"rendered":"ALTERNATIVE"},"content":{"rendered":"

\"ALTERNATIVE<\/p>\n<\/div>

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Desarrollo de una plataforma innovadora basada en un modelo de tejido card\u00edaco envejecido para evaluar la toxicolog\u00eda ambiental de mezclas de qu\u00edmicos<\/strong>.<\/p>\n

El proyecto ALTERNATIVE<\/strong> desarrolla una plataforma in vitro<\/em> con el objetivo de cultivar un tejido card\u00edaco humano funcional en 3D para evaluar la cardiotoxicidad de compuestos qu\u00edmicos y el impacto de sustancias t\u00f3xicas en la poblaci\u00f3n<\/strong>, especialmente en ancianos y personas con enfermedades cr\u00f3nicas.<\/p>\n

La nueva plataforma desarrollada permitir\u00e1 a los reguladores y la industria identificar, cuantificar y prevenir exposiciones cardiot\u00f3xicas a productos qu\u00edmicos industriales y farmac\u00e9uticos<\/strong> de una manera rentable. Adicionalmente, la implementaci\u00f3n de modelos computacionales permite a esta plataforma realizar predicciones sobre sustancias qu\u00edmicas y farmac\u00e9uticas, limitando el uso de animales de experimentaci\u00f3n, proporcionando informaci\u00f3n de escenarios reales sobre toxicidad y logrando una reducci\u00f3n significativa de los costes directos e indirectos asociados.<\/strong><\/p>\n

Por otro lado, el proyecto ALTERNATIVE tambi\u00e9n pretende incidir en la normativa europea y en la evaluaci\u00f3n de productos qu\u00edmicos industriales<\/strong> como fertilizantes o detergentes, o productos farmac\u00e9uticos.<\/p>\n

Eurecat participa en importantes tareas del proyecto a trav\u00e9s de su Unidad de Ciencias \u00d3micas<\/a>, que est\u00e1 realizando el an\u00e1lisis \u00f3mico en tejidos card\u00edacos para descubrir biomarcadores de toxicidad; la Unidad de Digital Health<\/a>, que realiza el modelado computacional de compuestos t\u00f3xicos; la Unidad de Impresi\u00f3n Funcional y Dispositivos Embebidos<\/a>, que se encarga de construir el sistema de electroestimulaci\u00f3n de la plataforma in vitro<\/em>, y la Unidad de Consultor\u00eda<\/a>, que se dedica a la gesti\u00f3n, impacto y explotaci\u00f3n de los datos.<\/p>\n

El proyecto, coordinado por Politecnico di Torino<\/a> (Italia), forma parte de las acciones del European Green Deal <\/em>\u201ctowards a zero-pollution ambition for a toxic free environment\u201d.<\/em><\/p>\n<\/div>

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\"ALTERNATIVE<\/span><\/div><\/div>

Datos generales<\/h3><\/span>
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Proyecto<\/strong><\/p>\n

ALTERNATIVE \u2013 Toxicolog\u00eda ambiental de mezclas de qu\u00edmicos mediante una plataforma innovadora basada en un modelo de tejido card\u00edaco envejecido.<\/p>\n

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Referencia del proyecto\u00a0<\/strong><\/p>\n

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H2020-LC-GD-2020-3 – 101037090<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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Programa y convocatoria<\/strong><\/p>\n

Proyecto financiado por el programa Horizon 2020 de la Uni\u00f3n Europea dentro de la convocatoria LC-GD-8-2-2020 – Fostering regulatory science to address combined exposures to industrial chemicals and pharmaceuticals: from science to evidence-based policies<\/em><\/p>\n<\/div>

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Web del proyecto<\/strong><\/p>\n

www.alternative-project.eu<\/a><\/p>\n<\/div>

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